Baclofen and the risk of fall and fracture in older adults: A real-world cohort study.
Yoseob Joseph HwangAlex R ChangDaniel J BrotmanLesley A InkerMorgan E GramsJung-Im ShinPublished in: Journal of the American Geriatrics Society (2023)
The risk of fall associated with baclofen was greater than tizanidine, but not compared to cyclobenzaprine in older adults. The risk of fracture was comparable among the older users of baclofen, tizanidine, and cyclobenzaprine. Our findings may inform risk-benefit considerations in the increasingly common clinical encounters where oral muscle relaxants are prescribed.