Polyoxovanadate-iodobodipy supramolecular assemblies: new agents for high efficiency cancer photochemotherapy.
Yaqi GuQi LiYichao HuangYingting ZhuYong-Ge WeiLaurent RuhlmannPublished in: Chemical communications (Cambridge, England) (2020)
Two novel polyoxovanadate-iodoBodipy supramolecular assemblies, named as (2I-BDP-C6)2V6 and (2I-BDP-C6)3V10, were first synthesized by the self-assembly of anionic hexavanadate and decavanadate with cationic iodoBodipy for photochemotherapy, respectively. The mechanisms for synergistic photochemotherapy of the anion-cation pairs were determined. In particular, (2I-BDP-C6)3V10 can effectively kill lung cancer cells (HepG2) by synergetic chemotherapy as well as photodynamic therapy.