Functional parcellation of the neonatal brain.

Michael J MyersAlyssa K Labonte Evan M Gordon Timothy O Laumann Jiaxin Cindy Tu Muriah D Wheelock Ashley N Nielsen Rebecca F Schwarzlose M Catalina Camacho Barbara B Warner Nandini Raghuraman Joan L Luby Deanna M Barch Damien A FairSteven E PetersenCynthia E Rogers Christopher D Smyser Chad M Sylvester

Published in: bioRxiv : the preprint server for biology (2023)

Neonatal cortical surface parcels derived based on abrupt changes in functional connectivity (FC) were highly homogenous and were validated in external neonatal datasets.Borders between cortical parcels were smoother (less abrupt) in group-average neonatal data compared to adults, likely due to increased heterogeneity in boundary location across individual neonates.Parcels derived from adults and older infants show poor fit with neonatal resting-state FC data, underscoring the need for a neonatal-specific parcellation.

Keyphrases

resting state
functional connectivity
big data
electronic health record
physical activity
machine learning
multiple sclerosis
single cell
artificial intelligence
rna seq