Real-world data from expanded access programmes in health technology assessments: a review of NICE technology appraisals.
Tobias B PolakDavid G J CucchiJoost van RosmalenCarin A Uyl-de GrootPublished in: BMJ open (2022)
NICE uses EA data in over one in five appraisals. In synthesis with evidence from well-controlled trials, data collected from EA programmes may meaningfully inform cost-effectiveness modelling.