Gender Differences in Efficacy and Safety of Direct Oral Anticoagulants in Atrial Fibrillation: Systematic Review and Network Meta-analysis.
Bruria Hirsh RaccahAmichai PerlmanDonna R ZwasSarit Hochberg-KleinReem MasarwaBruria Hirsh RaccahIlan MatokPublished in: The Annals of pharmacotherapy (2018)
Women treated with DOACs had a lower rate of major bleeding and higher rate of stroke and systemic emboli compared with men. Further investigation of DOACs, including differences between the DOACs in specific populations is warranted.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- venous thromboembolism
- heart failure
- polycystic ovary syndrome
- percutaneous coronary intervention
- pregnancy outcomes
- pregnant women
- coronary artery disease
- adipose tissue
- insulin resistance
- left ventricular