Cellular senescence in cancers: relationship between bone marrow cancer and cellular senescence.

Published in: Molecular biology reports (2022)

However, senescent cells increase in number as they age, which is very harmful over time. These cells extend into an older tissue for longer periods of time and form longer clusters in older tissues. Therefore, cellular senescence significantly contributes to aging.

Keyphrases

induced apoptosis
bone marrow
dna damage
endothelial cells
cell cycle arrest
physical activity
stress induced
gene expression
mesenchymal stem cells
middle aged
endoplasmic reticulum stress
community dwelling
signaling pathway