The Salivary Microbiome and Predicted Metabolite Production are Associated with Barrett's Esophagus and High Grade Dysplasia or Adenocarcinoma.

Quinn S Solfisburg Federico Baldini Brittany Baldwin-Hunter George I Austin Harry H Lee Heekuk Park Daniel E Freedberg Charles J Lightdale Tal Korem Julian A Abrams

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2023)

There is an association between oral dysbiosis and HGD/EAC. Further work is needed to establish the diagnostic, predictive and causal potential of this relationship.

Keyphrases

high grade
low grade
squamous cell carcinoma
locally advanced
radiation therapy
risk assessment