Comparing neoadjuvant chemotherapy with or without radiation therapy for pancreatic ductal adenocarcinoma: National Cancer Database cohort analysis.
Atsushi ObaY H Andrew WuKathryn L ColbornSana D KaramCheryl MeguidMohammed H Al-MusawiQuoc Riccardo BaoAna L GleisnerSteven AhrendtRichard D SchulickMarco Del ChiaroPublished in: The British journal of surgery (2022)
This study failed to show a survival benefit for NACRT over NAC alone, despite its association with negative margin resection. The significantly higher mortality in NACRT warrants further investigation into its efficacy in the treatment of pancreatic cancer.