Imaging, Pathology, and Immune Correlates in the Woodchuck Hepatic Tumor Model.
Michal Mauda-HavakukAndrew S MikhailMatthew F StarostElizabeth C JonesBaktiar KarimDavid E KleinerAri PartanenJuan A Esparza-TrujilloIvane BakhutashviliPaul G WakimMichael T KassinAndrew L LewisJohn W KaranianBradford J WoodWilliam F PritchardPublished in: Journal of hepatocellular carcinoma (2021)
Woodchucks chronically infected with WHV developed diverse hepatic tumor types with diagnostic imaging, pathology, and immune patterns comparable to that in humans. This unique animal model may provide a valuable tool for translation and validation of novel image-guided and immune-therapeutic investigations.
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