BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.

Sumit Agarwal Farrukh Afaq Prachi Bajpai Michael Behring Hyung-Gyoon Kim Amith Varambally Darshan S Chandrashekar Shajan Peter Sameer Al Diffalha Moh'd M Khushman Andreas Seeber Sooryanarayana Varambally Upender Manne

Published in: Molecular cancer research : MCR (2023)

FDA-approved small-molecule inhibitors of EZH2 can indirectly target BZW2 and because BZW2 functions as an oncogene, these inhibitors could serve as therapeutic agents for colorectal cancer.

Keyphrases

small molecule
protein protein
long non coding rna
long noncoding rna
drug administration