LEP rs7799039 and LEPR rs1137101 gene variants are not associated with clinical features in patients with metabolic syndrome in the Turkish population.

Marjan JabbarliNaci SenkalFatima Ceren TuncelYasemin OyaciMerve Guzel DirimMurat KoseSacide PehlivanAlpay Medetalibeyoglu

Published in: Laboratory medicine (2024)

Our results showed that the LEP rs7799039 and LEPR rs1137101 variants may be associated with both the risk of MetS development and clinical findings. Among the various contributors to MetS, a genetic predisposition is commonly recognized as the primary cause.

Keyphrases

copy number
metabolic syndrome
genome wide
type diabetes
insulin resistance
gene expression
adipose tissue