Comparative Analysis of Hyaluronidase-Mediated Degradation Among Seven Hyaluronic Acid Fillers in Hairless Mice.

Seong-Sung KwakKwang Ho YoonJin Hee KwonWon-Ho KangChang-Hoon RheeGi-Hyeok YangDeu John M CruzWoo-Chan Son

Published in: Clinical, cosmetic and investigational dermatology (2021)

All seven HA fillers show comparable susceptibility to hyaluronidase-mediated degradation. HA fillers with prolonged filler residence time may require a higher dose of hyaluronidase to achieve efficient degradation owing to tissue integration.

Keyphrases

hyaluronic acid
type diabetes
high fat diet induced
skeletal muscle
recombinant human