Variation of PEAR1 DNA methylation influences platelet and leukocyte function.

Benedetta IzziFrancesco GianfagnaWen-Yi YangKatrien CludtsAmalia De CurtisPeter VerhammeAugusto Di CastelnuovoChiara CerlettiMaria Benedetta DonatiGiovanni de GaetanoJan A StaessenMarc F HoylaertsLicia Iacoviellonull null

Published in: Clinical epigenetics (2019)

We report a significant link between epigenetic signatures in a platelet functional gene and inflammation-dependent platelet function variability measured in two independent cohorts.

Keyphrases

dna methylation
genome wide
gene expression
oxidative stress
copy number
peripheral blood