Prognostic association of plasma cell-free DNA-based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration-resistant prostate cancer patients.

Manish KohliJian LiMeijun DuDavid W HillmanScott M DehmWinston TanRachel CarlsonMichael B CampionLiguo WangLiewei WangHuijuan ZhangPeng ZhangDeepak KilariChiang-Ching HuangLiang Wang

Published in: Prostate cancer and prostatic diseases (2018)

CTCs and plasma cfDNA ARamp were observed to have equal prognostic value in mCRPC. Larger cohorts that incorporate molecular and clinical factors are needed to further refine prognosis in CRPC.

Keyphrases

circulating tumor cells
end stage renal disease
ejection fraction
squamous cell carcinoma
newly diagnosed
peritoneal dialysis
prognostic factors
locally advanced
radiation therapy
patient reported outcomes
single molecule