Argininyl-Fructosyl-Galactose: A Novel Amino Acid Derivative improves Cisplatin-induced Intestinal Toxicity via Reactive Oxygen Species- mediated Apoptosis Pathway.

Wei LiuYi-Nan ZhengShuang JiangShen RenShan TangJing ZhangZi WangWei Li

Published in: Current medicinal chemistry (2024)

The results clearly revealed AFGA as a potential multifunctional therapeutic agent with a clear protective effect against cisplatin-induced intestinal injury may be related to the PI3K/Akt signaling pathway.

Keyphrases

reactive oxygen species
signaling pathway
amino acid
drug delivery
oxidative stress
pi k akt
epithelial mesenchymal transition
cancer therapy
induced apoptosis
risk assessment
climate change
metal organic framework
oxide nanoparticles