Fast-Growing Alveolar Echinococcosis Following Lung Transplantation.
Clarisse DupontFrédéric GrenouilletJean-Yves MabrutFrédérique GayFlorence PersatMartine WallonJean-François MornexFrançois PhilitDamien DupontPublished in: Pathogens (Basel, Switzerland) (2020)
Alveolar echinococcosis is a rare but life-threatening infection caused by the parasite Echinococcus multilocularis. Its natural history is characterized by a slow parasitic growth over several years. Increased incidence and shorter development delay have been reported in immune-compromised patients. We report the reactivation of aborted lesions within 12 months of lung transplantation leading to a fast-growing aggressive hepatic lesion. Timely identification of alveolar echninococcosis allowed prompt albendazole treatment and radical surgery leading to a favorable outcome 42 months after transplantation. However, close clinical, serological and radiological monitoring is required to rule out relapses in the long term. The pre-existence of aborted self-limited lesions of alveolar echinococcosis and the possibility for their atypical rapid growth in patients undergoing profound immunosuppression should be known by healthcare providers, even if working in non-endemic areas.
Keyphrases
- healthcare
- patients undergoing
- end stage renal disease
- newly diagnosed
- ejection fraction
- minimally invasive
- extracorporeal membrane oxygenation
- chronic kidney disease
- risk factors
- prognostic factors
- peritoneal dialysis
- intellectual disability
- patient reported outcomes
- trypanosoma cruzi
- percutaneous coronary intervention
- patient reported
- smoking cessation