Microcirculation dynamics in systemic vasculitis: evidence of impaired microvascular response regardless of cardiovascular risk factors.

For the first time we have showed that patients with SVs exhibit impaired microvascular function and blunted reactivity after occlusion as this was demonstrated by LSCI technique. Therefore, skin microcirculation may be a useful, non-invasive method in patients with SVs for the early detection of microvascular dysfunction which is closely related to the high CV risk that these patients bear.