AbobotulinumtoxinA is effective in patients with urinary incontinence due to neurogenic detrusor overactivity regardless of spinal cord injury or multiple sclerosis etiology: Pooled analysis of two phase III randomized studies (CONTENT1 and CONTENT2).
Pierre DenysJuan Carlos CastañoRicardo Luis Vita NunesBarton WachsCristiano Mendes GomesGrigory KrivoborodovLe Mai TuGiulio Del-PopoloCatherine ThompsonClaire VilainMagali VolteauMichael Kennellynull nullPublished in: Neurourology and urodynamics (2022)
AboBoNT-A injections improved QoL, symptoms, and bladder function in patients with SCI or MS with bladder muscle overactivity that causes incontinence.
Keyphrases
- spinal cord injury
- phase iii
- urinary incontinence
- multiple sclerosis
- botulinum toxin
- open label
- double blind
- clinical trial
- placebo controlled
- neuropathic pain
- spinal cord
- phase ii
- mass spectrometry
- white matter
- skeletal muscle
- ultrasound guided
- study protocol
- sleep quality
- platelet rich plasma
- depressive symptoms
- physical activity
- urinary tract