Comparison Between the Physical Performance Test and the Clinical Frailty Score in Adult Patients With Chronic Kidney Disease Treated by Haemodialysis.
Andrew DavenportPublished in: Gerontology & geriatric medicine (2022)
Elderly patients with chronic kidney disease treated by haemodialysis are at increased risk of malnutrition and cachexia, becoming frail, with associated greater mortality. The physical performance test (PPT), using nine tasks to assess multiple domains of physical function is robust and reproducible, but time consuming, whereas the clinical frailty score (CFS) is more rapid. We compared the results from independent blinded observers in 22 haemodialysis patients, 16 (72.7%) male, mean age 65 ± 12.5 years. The PPT and CFS scores were highly correlated (r = -0.88, p < .001), with a high level of agreement (kappa score 0.91) for classifying patients as frail. Both scores were strongly associated with serum creatinine (PPT r=0.76, CFS r=-0.86, p < .001), hand grip strength (PPT r = 0.68, p = .001 CFS r = 0.64, p = .002), lean body mass index (PPT r = 0.50, p = .02, CFS r = -0.46, p = .038). We found that the CFS performed favourably compared to the PPT for haemodialysis patients in identifying and screening patients for frailty.
Keyphrases
- end stage renal disease
- chronic kidney disease
- peritoneal dialysis
- newly diagnosed
- ejection fraction
- body mass index
- prognostic factors
- type diabetes
- mental health
- immune response
- cardiovascular disease
- clinical trial
- young adults
- coronary artery disease
- community dwelling
- inflammatory response
- postmenopausal women
- uric acid
- middle aged