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Feasibility and first results of a prospective cohort study to investigate cisplatin-associated ototoxicity amongst cancer patients in South Africa.

Jessica PakenCyril Devadas GovenderMershen PillayBirhanu Teshome AyeleVikash Sewram
Published in: BMC cancer (2021)
Exposure to cisplatin treatment contributed to hearing loss in females with cervical cancer, highlighting the need for ototoxicity monitoring during chemotherapy treatments. Furthermore, the results indicate that it is possible to conduct prospective cohort studies, using a multidisciplinary approach in limited-resource environments with appropriate planning and training strategies, as this study was able to achieve its aim successfully.
Keyphrases
  • south africa
  • hearing loss
  • hiv positive
  • locally advanced
  • radiation therapy
  • virtual reality
  • replacement therapy
  • chemotherapy induced