Recent Developments in Nanomaterials-Based Drug Delivery and Upgrading Treatment of Cardiovascular Diseases.
Nura A MohamedIsra MareiSergio CrovellaHaissam Abou-SalehPublished in: International journal of molecular sciences (2022)
Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. However, despite the recent developments in the management of CVDs, the early and long outcomes vary considerably in patients, especially with the current challenges facing the detection and treatment of CVDs. This disparity is due to a lack of advanced diagnostic tools and targeted therapies, requiring innovative and alternative methods. Nanotechnology offers the opportunity to use nanomaterials in improving health and controlling diseases. Notably, nanotechnologies have recognized potential applicability in managing chronic diseases in the past few years, especially cancer and CVDs. Of particular interest is the use of nanoparticles as drug carriers to increase the pharmaco-efficacy and safety of conventional therapies. Different strategies have been proposed to use nanoparticles as drug carriers in CVDs; however, controversies regarding the selection of nanomaterials and nanoformulation are slowing their clinical translation. Therefore, this review focuses on nanotechnology for drug delivery and the application of nanomedicine in CVDs.
Keyphrases
- drug delivery
- cardiovascular disease
- end stage renal disease
- cancer therapy
- chronic kidney disease
- healthcare
- ejection fraction
- mental health
- adipose tissue
- coronary artery disease
- prognostic factors
- squamous cell carcinoma
- climate change
- emergency department
- risk assessment
- peritoneal dialysis
- adverse drug
- replacement therapy
- squamous cell
- cardiovascular events
- quantum dots
- cardiovascular risk factors
- electronic health record