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HLA-DRB5 overexpression promotes platelet reduction in immune thrombocytopenia mice model by facilitating MHC-II-mediated antigen presentation.
Yujuan Ren
Qianqian Ying
Ying Chen
Cong Liao
Anrong Li
Qidong Ye
Published in:
Acta haematologica (2024)
HLA-DRB5 overexpression upregulates MHC-II-mediated antigen presentation to CD8+ T cells, thus lowering PLT count in the ITP mice model.
Keyphrases
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transcription factor
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wild type