Case report: change of dominant strain during dual SARS-CoV-2 infection.
Andrei E SamoilovValeriia V KaptelovaAnna Y BukharinaOlga Y ShipulinaElena V KorneenkoStepan S SaenkoAlexander V LukyanovAntonina A GrishaevaAntonina A PloskirevaAnna S SperanskayaVasiliy G AkimkinPublished in: BMC infectious diseases (2021)
Our findings suggest that the patient was infected by two genetically distinct SARS-CoV-2 strains at the same time. One of the possible explanations is that the second infection was hospital-acquired. Change of the dominant strain ratio during disease manifestation could be explained by the advantage or higher virulence of the GR clade strain.