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Tumor-infiltrating lymphocyte transfusion in a patient with treatment refractory triple negative breast cancer.

Arielle JacoverYonaton ZarbivTal Kiedar HaranShira KleinShani BreuerRonen DurstBatia AvniSigal GrisariuPolina StepenskyMichal LotemOfra MaimonTamar Yablonski-Peretz
Published in: Cancer reports (Hoboken, N.J.) (2023)
This case is unique and peculiar regarding the treatment modality chosen, due to the extremely refractory disease the patient suffered from. After standard therapies rapidly failed, adoptive cell therapy was attempted with the infusion of TILs. This treatment has been shown effective in melanoma, however, there is an extreme paucity of data on other solid tumors, including TNBC. Although the patient ultimately demised presumably due to treatment side effects, brief clinical benefit was apparent. Further studies are warranted.
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