Genome-wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses.

Marco Napoli Avani A Deshpande Deepavali Chakravarti Kimal I Rajapakshe Preethi H Gunaratne Cristian Coarfa Elsa R Flores

Published in: Cancer research communications (2024)

The p63 isoforms, TAp63 and ΔNp63, control epithelial morphogenesis and tumorigenesis through the interaction with distinct transcription factors and the subsequent regulation of unique transcriptional programs.

Keyphrases

genome wide
transcription factor
dna methylation
copy number
oxidative stress
genome wide identification
gene expression
public health
dna binding
heat shock