Login / Signup
Inflammation in cerebral ischemia reperfusion improved by avanafil via nod-like receptor protein-3 inflammasome: an experimental study in rats.
Huseyin Bekmez
Mehmet Nuri Kocak
Taha Tavaci
Hamza Halici
Erdem Toktay
Muhammet Celik
Hamit Harun Bagci
Published in:
Brain injury (2024)
Avanafil, was found to have ameliorated inflammatory response and cellular injury caused by CI/R. The mRNA expression of IL-1β, NLRP3, and TNF-α decreased in the I/R groups and approached the control group levels with a high dose of avanafil.
Keyphrases
</>
high dose
inflammatory response
oxidative stress
rheumatoid arthritis
low dose
lipopolysaccharide induced
subarachnoid hemorrhage
binding protein
lps induced
protein protein
amino acid
small molecule
nlrp inflammasome
cerebral ischemia
immune response
brain injury
cerebral blood flow