NEOADJUVANT CHEMORADIOTHERAPY FOLLOWED BY TRANSHITAL ESOPHAGECTOMY IN LOCALLY ADVANCED ESOPHAGEAL SQUAMOUS CELL CARCINOMA: IMPACT OF PATHOLOGICAL COMPLETE RESPONSE.

Iuri Pedreira Fillardi Alves Valdir Tercioti Junior João de Souza Coelho Neto José Antonio Possatto Ferrer José Barreto Campello Carvalheira Eduardo Baldon Pereira Luiz Roberto Lopes Nelson Adami Andreollo

Published in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2022)

There was no statistical difference in overall survival and disease-free survival for patients who had a complete pathological response to neoadjuvant. Patients submitted to the therapeutic regimen with Paclitaxel and Carboplastin, showed a significant difference with better complete pathological response and disease progression. New parameters are indicated to clarify the real value in survival, from the complete pathological response to neoadjuvant, in esophageal cancer.

Keyphrases

locally advanced
rectal cancer
free survival
neoadjuvant chemotherapy
squamous cell carcinoma
radiation therapy
phase ii study
lymph node
ejection fraction
prognostic factors
clinical trial
patient reported outcomes
robot assisted
study protocol
peritoneal dialysis