Primary fibroblasts derived from sporadic amyotrophic lateral sclerosis patients do not show ALS cytological lesions.
Philippe CodronJulien CassereauPatrick Vourc'hCharlotte Veyrat-DurebexHélène BlascoSelma KaneVincent ProcaccioFranck LetournelChristophe VernyGuy LenearsPascal ReynierArnaud ChevrollierPublished in: Amyotrophic lateral sclerosis & frontotemporal degeneration (2018)
ALS cytological lesions are absent in patient-derived fibroblasts and thus cannot contribute as diagnostic nor prognostic markers of the disease.