Adverse Events Associated with Universal versus Targeted Antifungal Prophylaxis among Lung Transplant Recipients-A Nationwide Cohort Study 2010-2019.

Cornelia Geisler CroneSigne Marie WulffJannik Helweg-LarsenPia BredahlMaiken Cavling Arendrup Michael PerchMarie Helleberg

Published in: Microorganisms (2022)

Universal voriconazole prophylaxis was associated with high rates of discontinuation, mainly caused by hepatotoxicity. In comparison to the targeted posaconazole period, more patients had low CNI levels and acute rejection in the universal voriconazole period.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
cancer therapy
drug induced
liver failure
peritoneal dialysis
prognostic factors
candida albicans