Dienogest does not augment the gene expression of adhesion molecules, MCP-1, and monocyte adherence in human endothelial cells.
Nanami TaharaFumitake ItoMari KawamataMasahiro OtaniTaisuke MoriPublished in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2024)
DNG had no effect on the mRNA expression of adhesion molecules and cytokines in HUVECs, as well as the monocyte adhesion to HUVECs, suggesting that DNG can be explored as an alternative to MPA for HRT.