Heparin-binding protein as a biomarker for the diagnosis of sepsis in the intensive care unit: a retrospective cross-sectional study in China.

Lingyun ZuoXiaoyun LiLuhao WangHao YuanZihuai LiaoSi ZhouJianfeng WuXiangdong Guan Yongjun Liu

Published in: BMJ open (2024)

HBP could serve as a biomarker for the diagnosis of sepsis in the ICU. Compared with single indicators, the sepsis diagnostic model constructed using HBP, PCT, CRP, IL-6 and SOFA further enhanced the diagnostic performance of sepsis.

Keyphrases

intensive care unit
septic shock
acute kidney injury
binding protein
venous thromboembolism
mechanical ventilation