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Carbon-ion radiotherapy versus radiofrequency ablation as initial treatment for early-stage hepatocellular carcinoma.

Naoto FujitaNaoya KanogawaHirokazu MakishimaSadahisa OgasawaraSusumu MarutaYotaro IinoYuki ShikoHiroaki KanzakiKeisuke KorokiKazufumi KobayashiSoichiro KiyonoMasato NakamuraTakayuki KondoShingo NakamotoTetsuhiro ChibaMasaru WakatsukiEi ItobayashiMasamichi ObuYoshihiro KomaRyosaku AzemotoYohei KawasakiJun KatoHiroshi TsujiNaoya Kato
Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2022)
Carbon-ion radiotherapy provided a lower cumulative intrasubsegmental recurrence rate, but a comparable cumulative local recurrence rate, stage progression-free survival, and OS compared to RFA. Thus, C-ion RT appears to be one of the effective treatment options for early-stage HCC when RFA is deemed not indicated.
Keyphrases
  • early stage
  • radiofrequency ablation
  • free survival
  • sentinel lymph node
  • radiation therapy
  • locally advanced
  • combination therapy