Intermittent Short-Term Infusion vs. Continuous Infusion of Piperacillin: Steady State Concentrations in Porcine Cervical Spine Tissue Evaluated by Microdialysis.
Elisabeth Krogsgaard PetersenPelle HanbergMartin KnudsenSara Kousgaard TøstesenAndrea René JørgensenKristina Öbrink-HansenKjeld SøballeMaiken StillingMats BuePublished in: Antibiotics (Basel, Switzerland) (2022)
T > MIC compared to STI infusion across the investigated tissues and targets. CI should therefore be considered in spondylodiscitis cases requiring piperacillin treatment.