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Intermittent Short-Term Infusion vs. Continuous Infusion of Piperacillin: Steady State Concentrations in Porcine Cervical Spine Tissue Evaluated by Microdialysis.

Elisabeth Krogsgaard PetersenPelle HanbergMartin KnudsenSara Kousgaard TøstesenAndrea René JørgensenKristina Öbrink-HansenKjeld SøballeMaiken StillingMats Bue
Published in: Antibiotics (Basel, Switzerland) (2022)
T > MIC compared to STI infusion across the investigated tissues and targets. CI should therefore be considered in spondylodiscitis cases requiring piperacillin treatment.
Keyphrases
  • low dose
  • gene expression
  • men who have sex with men
  • mass spectrometry
  • high resolution
  • combination therapy
  • replacement therapy