Hypothalamic CRF1 receptor mechanisms are not sufficient to account for binge-like palatable food consumption in female rats.

Maria Vittoria Micioni Di BonaventuraMassimo UbaldiMaria Elena GiusepponiKenner C RiceMaurizio MassiRoberto CiccocioppoCarlo Cifani

Published in: The International journal of eating disorders (2017)

These findings demonstrate that extra-hypothalamic CRF1 receptors, rather than those involved in endocrine functions, are involved in binge eating and the crucial role of CRF receptors in CeA. CRF1 receptor antagonism may represent a novel pharmacological treatment for binge-related eating disorders.

Keyphrases

physical activity
weight loss
binding protein
risk assessment
smoking cessation