High glucose induces inflammatory responses in HepG2 cells via the oxidative stress-mediated activation of NF-κB, and MAPK pathways in HepG2 cells.
Ghodratollah PanahiParvin PasalarMina ZareRosario RizzutoReza MeshkaniPublished in: Archives of physiology and biochemistry (2018)
Our results indicated that HG-induced inflammation is mediated through the generation of ROS and activation of the MAPKs and NF-kB signalling pathways in HepG2 cells.