P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages.

Yu ZhangPatrick BabczykAndreas PanskyMatthias Ulrich KassackEdda Tobiasch

Published in: International journal of molecular sciences (2020)

Purinergic 2 receptors play a crucial role during the differentiation towards endothelial and smooth muscle cell lineages. Some highly selective and potent artificial purinergic 2 ligands can control hMSC differentiation, which might improve the use of adult stem cells in cardiovascular tissue engineering in the future.

Keyphrases

smooth muscle
stem cells
tissue engineering
endothelial cells
cell therapy
single cell
current status
anti inflammatory
high glucose
vascular endothelial growth factor