Impact of hormonal contraception and weight loss on high-density lipoprotein cholesterol efflux and lipoprotein particles in women with polycystic ovary syndrome.
Anuja DokrasMartin PlayfordPenny M Kris-EthertonAllen R KunselmanChristy M StetterNancy I WilliamsCarol L GnatukStephanie J EstesDavid B SarwerKelly C AllisonChristos CoutifarisNehal MehtaRichard S LegroPublished in: Clinical endocrinology (2017)
Oral contraceptive pills use is associated with improved HDL-C function and a concomitant atherogenic LDL-C profile. Combination of a Lifestyle program with OCP use improved HDL-C function and mitigated adverse effects of OCP on lipoproteins. Our study provides evidence for use of OCP in overweight/obese women with PCOS when combined with Lifestyle changes.
Keyphrases
- weight loss
- polycystic ovary syndrome
- bariatric surgery
- roux en y gastric bypass
- gastric bypass
- metabolic syndrome
- low density lipoprotein
- physical activity
- glycemic control
- insulin resistance
- weight gain
- obese patients
- cardiovascular disease
- type diabetes
- emergency department
- adipose tissue
- pregnant women
- skeletal muscle
- cervical cancer screening
- adverse drug