Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure.
Eva C M VitucciAlysha E SimmonsElizabeth M MartinShaun D McCulloughPublished in: Particle and fibre toxicology (2024)
exposure. Ultimately, these data expand our current understanding of respiratory disease development following particle exposures and illustrate the utility of multicellular in vitro systems for investigating respiratory tract health.