Predictive Factors for Efficacy and Safety of Prophylactic Theophylline for Extubation in Infants with Apnea of Prematurity.

Tomoko KondoYuki KondoYuji OritaFumi MitaraiYoichi IshitsukaMitsuru IrikuraYoshihiro ShimodozonoTsutomu DouchiYasuo TakedaTetsumi Irie

Published in: PloS one (2016)

Physicians need to be aware of the possibility that theophylline fails to produce therapeutic effects for extubation in infants aged less than 31.1 weeks old, and adverse reactions can easily develop when theophylline is administered soon after birth.

Keyphrases

cardiac surgery
mechanical ventilation
gestational age
primary care
obstructive sleep apnea
preterm infants
respiratory failure
acute kidney injury
intensive care unit
pregnant women
acute respiratory distress syndrome