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CT Body Composition of Sarcopenia and Sarcopenic Obesity: Predictors of Postoperative Complications and Survival in Patients with Locally Advanced Esophageal Adenocarcinoma.

Fehrenbach UliTilo WuenschPia GabrielLaura SeggerTakeru YamaguchiTimo Alexander AuerNick Lasse BeetzChristian DeneckeDino KröllJonas RaakowSebastian KnitterSascha ChopraPeter C Thuss-PatienceJohann PratschkeBernd HammMatthias BieblDominik Geisel
Published in: Cancers (2021)
CT body composition imaging biomarkers can identify high-risk patients with locally advanced esophageal cancer undergoing surgery. Sarcopenic patients have a higher risk of major complications, and patients with sarcopenic obesity are more prone to postoperative pneumonia. Sarcopenia and sarcopenic obesity are both subsequently associated with a prolonged hospitalization. Low preoperative muscle mass and its decrease during the postoperative follow-up are associated with lower DFS and OS.
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