Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity.

Iago Pinal-FernandezMaria Casal-DominguezJohn A CarrinoArash H LahoutiPari BasharatJemima AlbaydaJulie J PaikShivani AhlawatSonye K DanoffThomas E LloydAndrew L MammenLisa Christopher-Stine

Published in: Annals of the rheumatic diseases (2016)

Compared with patients with DM or PM, IMNM is characterised by more widespread muscle involvement. Anti-SRP-positive patients have more severe muscle involvement than anti-HMGCR-positive patients.

Keyphrases

end stage renal disease
skeletal muscle
ejection fraction
chronic kidney disease
newly diagnosed
magnetic resonance imaging
prognostic factors
peritoneal dialysis
systemic lupus erythematosus
type diabetes
patient reported outcomes
metabolic syndrome
adipose tissue
risk assessment
air pollution