COVID-19 vaccine impact on rates of SARS-CoV-2 cases and post vaccination strain sequences among healthcare workers at an urban academic medical center: a prospective cohort study.

Tara C BoutonSara LodiJacquelyn TurcinovicSarah E WeberEmily QuinnCathy KornJacqueline SteinerElissa M Schechter-PerkinsElizabeth DuffyElizabeth J RaganBradford P TaylorBeau SchaefferNancy MillerRavin DavidoffWilliam P HanageJohn ConnorCassandra PierreKaren R Jacobson

Published in: medRxiv : the preprint server for health sciences (2021)

Cases of SARS-CoV-2 among health care workers dropped rapidly with COVID-19 vaccination. Sequencing 48 breakthrough infections (overwhelmingly in 14 days after 1st dose) showed no clear sign of any differences in spike protein compared with time-matched, unvaccinated control sequences.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
single cell
protein protein
amino acid
genetic diversity