The walnut-derived peptide TW-7 improves mouse parthenogenetic embryo development of vitrified MII oocytes potentially by promoting histone lactylation.
Yaozong WeiBo PanJianpeng QinBeijia CaoTianyi LvJiangfeng YeAo NingKunlin DuXiangyi ChenShuqi ZouShengqin ZangGuozhi YuTianzeng SongQiuxia LiangGuang-Bin ZhouPublished in: Journal of animal science and biotechnology (2024)
Our findings revealed the mechanism of oxidative stress inducing repressed development of PA embryos from vitrified mouse MII oocytes and found a potent and easy-obtained short peptide that could significantly rescue the decreased developmental potential of vitrified oocytes, which would potentially contribute to reproductive medicine, animal protection, and breeding.