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Ex vivo assays to predict enhanced chemosensitization by hyperthermia in urothelial cancer of the bladder.

Nathalie van den TempelKishan A T NaipalAnja RaamsDik C van GentMartine FranckenaJoost L BoormansRoland Kanaar
Published in: PloS one (2018)
The cytochrome C assay and the RAD51 focus formation assay are both feasible on freshly obtained bladder tumors, and could serve to predict the efficacy of hyperthermia together with cytotoxic agents, such as MMC or cisplatin.
Keyphrases
  • high throughput
  • urinary tract
  • spinal cord injury
  • papillary thyroid
  • dna damage
  • dna repair
  • squamous cell
  • high grade
  • single cell
  • squamous cell carcinoma
  • oxidative stress