J-shape relation of blood pressure reduction and outcome in acute intracerebral hemorrhage: A pooled analysis of INTERACT2 and ATACH-II individual participant data.

Xia WangGian Luca Di TannaTom James MoullaaliRenee' H MartinVirginia B ShipesThompson G RobinsonJohn ChalmersJose I SuarezAdnan I QureshiYuko Y PaleschCraig S Anderson

Published in: International journal of stroke : official journal of the International Stroke Society (2022)

A moderate degree of rapid SBP lowering is associated with improved functional outcome after ICH, but large SBP reductions over 1 h (e.g. from > 200 to target < 140 mmHg) were associated with reduction, or reversal, of any such benefit.

Keyphrases

blood pressure
liver failure
brain injury
electronic health record
respiratory failure
high intensity
big data
hypertensive patients
heart rate
drug induced
aortic dissection
intensive care unit
machine learning
loop mediated isothermal amplification
deep learning
weight loss
artificial intelligence