Rapid Flow Cytometry-Based Assay for the Functional Classification of MEFV Variants.

Yoshitaka Honda Yukako Maeda Kazushi IzawaTakeshi ShibaTakayuki TanakaHaruna NakasekoKeisuke NishimuraHiroki MukoyamaMasahiko Isa-NishitaniTakayuki MiyamotoHiroshi NihiraHirofumi ShibataEitaro HiejimaOsamu OharaJunko TakitaTakahiro YasumiRyuta Nishikomori

Published in: Journal of clinical immunology (2021)

Our assay facilitates a rapid and comprehensive assessment of the pathogenicity of MEFV variants and contributes to a refined definition of PAAD subtypes.

Keyphrases

flow cytometry
copy number
high throughput
loop mediated isothermal amplification
machine learning
deep learning
single cell
quantum dots
clinical evaluation