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Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials.

Peiran ZhangJoseph RufoChuyi ChenJian-Ping XiaZhenhua TianLiying ZhangNanjing HaoZhanwei ZhongYuyang GuKrishnendu ChakrabartyTony Jun Huang
Published in: Nature communications (2021)
The ability to precisely manipulate nano-objects on a large scale can enable the fabrication of materials and devices with tunable optical, electromagnetic, and mechanical properties. However, the dynamic, parallel manipulation of nanoscale colloids and materials remains a significant challenge. Here, we demonstrate acoustoelectronic nanotweezers, which combine the precision and robustness afforded by electronic tweezers with versatility and large-field dynamic control granted by acoustic tweezing techniques, to enable the massively parallel manipulation of sub-100 nm objects with excellent versatility and controllability. Using this approach, we demonstrated the complex patterning of various nanoparticles (e.g., DNAs, exosomes, ~3 nm graphene flakes, ~6 nm quantum dots, ~3.5 nm proteins, and ~1.4 nm dextran), fabricated macroscopic materials with nano-textures, and performed high-resolution, single nanoparticle manipulation. Various nanomanipulation functions, including transportation, concentration, orientation, pattern-overlaying, and sorting, have also been achieved using a simple device configuration. Altogether, acoustoelectronic nanotweezers overcome existing limitations in nano-manipulation and hold great potential for a variety of applications in the fields of electronics, optics, condensed matter physics, metamaterials, and biomedicine.
Keyphrases
  • photodynamic therapy
  • high resolution
  • light emitting
  • quantum dots
  • stem cells
  • mesenchymal stem cells
  • bone marrow
  • high speed
  • risk assessment
  • single molecule