MALT-1 as a novel therapeutic target for adult T-cell leukemia.

Published in: European journal of haematology (2020)

MALT-1 plays an important regulatory role in NF-κB signaling during ATL-genesis, and targeting MALT-1 is a promising therapeutic strategy for this disease.

Keyphrases

signaling pathway
acute myeloid leukemia
bone marrow
transcription factor
lps induced
oxidative stress
cancer therapy
immune response