Molecular Classification of Lymph Node Metastases Subtypes Predict for Survival in Head and Neck Cancer.

Lei HuangOdile DavidRobert J CabayKlara Valyi-NagyVirgilia MaciasRong ZhongBarry WenigLawrence FeldmanRalph R WeichselbaumMichael T Spiotto

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

The transcriptional profiles of LNMs better predict outcomes than transcriptional profiles of primary tumors. The LNMs display site-specific subtypes associated with worse disease control and survival across multiple cancer types.

Keyphrases

lymph node
gene expression
transcription factor
papillary thyroid
free survival
machine learning
deep learning
neoadjuvant chemotherapy
heat shock
type diabetes
squamous cell carcinoma
sentinel lymph node
early stage
young adults
metabolic syndrome
radiation therapy
lymph node metastasis
heat shock protein