Small duct and large duct type intrahepatic cholangiocarcinoma reveal distinct patterns of immune signatures.
Simon BernatzFalko SchulzeJulia BeinKatrin BankovScherwin MahmoudiLeon D GrünewaldVitali KochAngelika StehleAndreas A SchnitzbauerDirk WalterFabian FinkelmeierStefan ZeuzemThomas J VoglPeter J WildMaximilian N KinzlerPublished in: Journal of cancer research and clinical oncology (2024)
Immune patterns differed in SD-iCCA versus LD-iCCA. We identified potential biomarker candidate genes, including CRP, CEACAM6, DMBT1, and various complement factors that could be explored for augmented diagnostics and treatment decision-making.